rs63750828
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Hereditary Nonpolyposis Colorectal Neoplasms
A
0.700
GeneticVariation
CLINVAR
Thyroid cancer in a patient with Lynch syndrome - case report and literature review.
28769567
2017
rs63750828
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Hereditary Nonpolyposis Colorectal Neoplasms
A
0.700
GeneticVariation
CLINVAR
Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing.
26681312
2016
rs63750828
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Hereditary Nonpolyposis Colorectal Neoplasms
A
0.700
GeneticVariation
CLINVAR
Oligonucleotide-directed mutagenesis screen to identify pathogenic Lynch syndrome-associated MSH2 DNA mismatch repair gene variants.
26951660
2016
rs63750828
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Hereditary Nonpolyposis Colorectal Neoplasms
A
0.700
GeneticVariation
CLINVAR
Genetic diagnosis of high-penetrance susceptibility for colorectal cancer (CRC) is achievable for a high proportion of familial CRC by exome sequencing.
25559809
2015
rs63750828
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Hereditary Nonpolyposis Colorectal Neoplasms
A
0.700
GeneticVariation
CLINVAR
UMD-MLH1/MSH2/MSH6 databases: description and analysis of genetic variations in French Lynch syndrome families.
23729658
2013
rs63750828
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Hereditary Nonpolyposis Colorectal Neoplasms
A
0.700
GeneticVariation
CLINVAR
Cancer risks associated with germline mutations in MLH1, MSH2, and MSH6 genes in Lynch syndrome.
21642682
2011
rs63750828
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Hereditary Nonpolyposis Colorectal Neoplasms
A
0.700
GeneticVariation
CLINVAR
Mechanisms of pathogenicity in human MSH2 missense mutants.
18951462
2008
rs63750828
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Hereditary Nonpolyposis Colorectal Neoplasms
A
0.700
GeneticVariation
CLINVAR
Functional characterization of pathogenic human MSH2 missense mutations in Saccharomyces cerevisiae.
17720936
2007
rs63750828
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Hereditary Nonpolyposis Colorectal Neoplasms
A
0.700
GeneticVariation
CLINVAR
Pathogenicity of MSH2 missense mutations is typically associated with impaired repair capability of the mutated protein.
17101317
2006
rs63750828
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Hereditary Nonpolyposis Colorectal Neoplasms
A
0.700
GeneticVariation
CLINVAR
Spectrum and frequencies of mutations in MSH2 and MLH1 identified in 1,721 German families suspected of hereditary nonpolyposis colorectal cancer.
15849733
2005
rs63750828
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Hereditary Nonpolyposis Colorectal Neoplasms
A
0.700
GeneticVariation
CLINVAR
Routine testing for mismatch repair deficiency in sporadic colorectal cancer is justified.
16175654
2005
rs63750828
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Hereditary Nonpolyposis Colorectal Neoplasms
A
0.700
GeneticVariation
CLINVAR
Cancer risk in 348 French MSH2 or MLH1 gene carriers.
12624141
2003